Tested:
Fallout 4 - OK
Fallout Shelter - OK (XP x64 too)
BeamNG.Drive - OK
How to Survive - OK
Rise of Tomb Raider - Fail (TryAcquireSRWLockExclusive could not be located in the dynamic link library Kernel32.dll)
Tom Clancy's The Division - Fail (TryAcquireSRWLockExclusive could not be located in the dynamic link library Kernel32.dll)
Steep - Fail (TryAcquireSRWLockExclusive could not be located in the dynamic link library Kernel32.dll)
State of Decay YOSE - Fail (TryAcquireSRWLockExclusive could not be located in the dynamic link library Kernel32.dll)
+ Also you can install nVidia Display Drivers version 372.54, official site says its supports only Win7+, but it still works on Vista.