Out of the box, if using GPT format (even on a BIOS level), Windows 8 is going to automatically create the MSR and boot partitions. In this case, if you are using GPT on BIOS, you'd get a 2TB max GPT volume (even if the disk is larger) but the OS won't be able to boot because Windows 8 cannot write the boot files for a GPT disk on BIOS. But it is possible to manually install Windows 8 (not using Setup, but using DISM) to a GPT disk on BIOS, as long as the two other partitions aren't created. That, however, isn't a supported method of installing an OS on GPT.