What you want to know is here: http://win2k3.MSFN.org/ All you applications will work, but many peripherals will not (mouse drivers, digital camera drivers, scanner drivers). Win2k3 was designed to be a Server, not a Workstation, but it can be tweaked to perform more like a workstation. I used an evaluation copy for several months. If you want to try out your copy, create a separate partition and configure for a multi-boot (I use Partition Magic/Boot Magic).