What program or file do you try to open to produce that error? Is ghhle.exe on your hard drive, and what program was it for? (I've searched on google, nothing there) If you're still unsure what registry entries to delete, change the file associations for the extension instead (if it's a file!) edit: Just read topic after posting this, ok.. go into Start > Run > MSCONFIG and look for references to ghhle.exe in the startup tab or any of the other similar error messages you received. Delete them.