w00t I have blocked so many individual sites over the years that I have now begun to block email based on regional netspace. This will differ with your specific area because spammers tend to spam out of their specific netspace. As if the don't want to dirty the water they swim in. Earthlink spammers don't usually spam Earthlink addresses, etc. etc. Personally I block all of 200.x.x.x, 201.x.x.x, 202.x.x.x, 203.x.x.x, 210.x.x.x, 211.x.x.x plus many ranges in other netblocks that prove to be spam friendly. It's not perfect but it kills 80% of my spam.