But that's because the middle-click is practically useless to me (it's hardly mandatory in the vast majority of all software, and my guess is that most people do not use it) while the double-click is ubiquitous. So, replacing it with the wheel-click, saves countless clicks and protects healthy hands (and doesn't overwork problematic hands like mine). The wheel-click could be assigned to another, less prominent mouse button, but that won't help people who don't own multiple-button mouses ("mice" sounds wrong ) .