i use on s***(wxp) emule, emule+, dc+ & BitComet but from month i use p2p on my homie linux router and i found good p2p client mldonkey (it comes with Edonkey,Overnet,Bittorent,Shareaza,Gnutella,DC etc.) ALL in ONE!
good client but you must know smth aout linux/telnet.. of course mldonkey on linux is WWW Gui based and Gui on X (i thing on GTK), telnet and Wap
Im running mldonkey on Debian/Sid - unstable - the pakage is "mldonkey-server".