Autoit does only lock the keyboard in a limited way. If you press Ctrl-Alt-Del, the user unlocks the keyboard and mouse. Look at this utility from Systemintegrasjon (by me, really): http://www.sysint.no/en/download.aspx. Go to the KeyboardLock section on that page. Read more at this page: http://www.sysint.no/nedlasting/KeyboardLock.htm You may load the driver dynamically using DrvLoad.exe /l KbLock.sys, and then lock the keyboard by creating the registry key HKLM\Software\Systemintegrasjon\KeyboardLock\LockAll, to unlock just delete the key again.