I have a slight variation of this issue. Having once learned the hardway that .NET Framework security updates are best to be installed separately, I downloaded KB2572078 via windows update first. Before I proceeded with the next update for NET Framework 4 this time around, I suddenly realized an event id 1103 in the event viewer. ".NET Runtime Optimization Service (clr_optimization_v2.0.50727_32) - Tried to start a service that wasn't the latest version of CLR Optimization service. Will shutdown" Now what? There seems to be a discussion on the web of the similar event, that dates back to 2010 and KB976569 installation issues, so I am not sure this is the same. Would appreciate any clues how to deal with it.