Have just had exactly the same problem with a colleague's Vista Home Premium comp. After several attempts via windows explorer, the drive will read the DVD, but at the bottom of the right hand pane is: Files ready to be written to CD (& it is always desktop.ini) Delete the file & the drive behaves as normal (except Autoplay does not work as requested via Control Panel - Autoplay options). He had been burning a CD with Roxio, prior to the problem, so I'm guessing the CD had not been finalised & had left a unanswered request. Hope someone has a better solution? Regards, Max.