I initially thought it might be an issue with VLite, but as I mentioned previously, I also set up a new pc using the original Vista Ultimate x64 disc, no integrated hotfixes, and no use of Vlite. Once installed I updated it via windows update. Then once that was done and the pc had rebooted, I manually installed KB941649, and it stuck on configuring updates. Rebooting made it just hang on the loading screen.