I have been running the Reliability and performance tool and I am also running Vista home Prem with MSE installed. I keep getting this : The Security Center has reported that on-access spyware scanning is disabled. Either on-access scanning is disabled, or the anti-spyware application is not recognized. MSE has everything updated and is working as it should be. Any help here or is it due to the layering of windows defender on top of MSE that causes the conflict?