usually i get skype.msi for business on skype website and use their own command: start /wait msiexec /i SkypeSetup.msi INSTALLLEVEL=1 STARTSKYPE=FALSE ALLUSERS=1 TRANSFORMS=:removeStartup.mst TRANSFORMS=:removeDesktopShortcut.mst /qr this result in no skype plugin manager, no toolbar, no ie and ff addon