Not really. If you look at socket 478, alot of older boards do not support prescott processors (ones with 845 chipset). There are also some that do/dont support HT, etc. Depending on the chipset again, some LGA775 boards do not support dual core, while others do. Seeing as this is one of the standard older Prescott proccessors, it should work on any LGA775 board with any chipset.